Microdose GLP-1
A Different Goal Than Weight Loss
Microdose GLP-1 protocols target body composition, not rapid scale change. Clinically supervised, dose-titrated to the individual.
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Microdosing GLP-1 is a low-dose, clinician-supervised approach to using semaglutide or tirzepatide for body recomposition rather than significant weight loss. The protocol uses doses well below the trial-dose escalation curve and adjusts based on composition signals, not scale change.
For patients pursuing recomposition, the goal is a sustainable appetite signal without the gastrointestinal disruption associated with standard-dose escalation. Eligibility is determined individually by a licensed clinician.
Compare
Standard-dose Semaglutide
Full-dose escalation for significant weight loss — see the standard protocol.
Compare
Standard-dose Tirzepatide
Dual-receptor protocol for the most clinically intensive weight-loss track.
Sibling hub
Body Recomposition
Peptide stacks paired with microdose GLP-1 — the full recomposition protocol.
Read more
Microdosing on the blog
Plain-language posts on dosing, candidacy, and timeline.
FAQ
Common questions
What is microdosing GLP-1?
Microdosing GLP-1 means using a low weekly dose of a GLP-1 receptor agonist (semaglutide or tirzepatide) to nudge appetite signaling without producing the strong appetite suppression and gastrointestinal side effects associated with the standard escalation curve. The dose is typically a fraction of the doses used in the published weight-loss trials, and the cadence is calibrated by a clinician to the individual patient.
How is microdosing different from a standard GLP-1 protocol?
Standard GLP-1 protocols escalate weekly doses over several months toward a target dose designed to produce significant weight loss. Microdose protocols start lower and stay lower — the goal is sustainable composition change, not rapid scale change. Day-to-day, microdose patients typically describe a quieter appetite signal and less gastrointestinal disruption than patients on the standard escalation curve.
Who is microdosing GLP-1 a good fit for?
Microdosing tends to fit patients who are already lean or near a healthy BMI, who train consistently, and who want to refine body composition rather than reset it. It is often paired with a foundational peptide protocol (NAD+, sermorelin, B12/MIC) so the recomposition signal is supported by recovery and energy work, not just appetite suppression. Eligibility is determined individually by your prescribing clinician.
Who is microdosing NOT a good fit for?
Patients whose clinical picture calls for significant weight loss are typically better served by standard-dose protocols, where the dose-response data is much stronger. Microdosing is not appropriate for patients with certain thyroid conditions, pancreatitis history, or other contraindications. A clinician will make this call during intake based on goals, history, and labs.
What kind of results should I expect on a microdose protocol?
Because the goal is composition rather than scale, the monitoring cadence emphasizes things the scale does not capture — waist circumference, training session quality, and patient-reported energy and recovery. The scale is still tracked, but it is not the primary signal. Individual results vary, and TelePeptide does not promise any specific outcome.
Are compound semaglutide and tirzepatide the same as the brand-name versions?
Compounded semaglutide and tirzepatide use the same active peptides as the brand-name FDA-approved versions, but they are formulated by licensed 503A pharmacies and prescribed individually based on medical necessity. Compounded medications are not FDA-approved. Compounded versions are not equivalent to brand-name FDA-approved drugs.
How does TelePeptide price microdose protocols?
Microdose GLP-1 protocols are priced the same as the standard-dose program. The clinician determines the dose, not the price tier. Founder-rate pricing is locked in.
How do I get started?
Complete the online intake. A licensed clinician will review your goals, training history, and medical context within 48 hours and recommend a microdose, standard-dose, or alternative protocol — or determine you are not a candidate.
Next Step
See if microdosing is right for you
A licensed clinician will review your goals and recommend the right protocol — peptide wellness, recomposition, or supervised weight loss. No insurance, no waiting room.
Compounded medications are prepared by licensed 503A pharmacies. Prescribing decisions are made solely by licensed clinicians based on individual medical necessity. These statements have not been evaluated by the FDA. Compounded medications are not FDA-approved.